Recombinant Human CD200R1 (Ala27-Leu266) with C-terminus Fc-tag is expressed in CHO cell and conjugated to APC.
accession number
Q8TD46
Molecular Weight
The protein has a predicted molecular weight of 53.1 kDa. Under DTT-reducing conditions, it migrates at approximately 80-110 kDa on SDS-PAGE prior to conjugation.
Affinity Tag
C-Fc
Formulation
1xPBS buffer, pH7.4, 0.09% NaN3 with a carrier protein
Endotoxin level
Not tested
Protein Concentration
25µg size is bottled at 0.1mg/mL concentration. 100 µg size is bottled at lot specific concentration.
Storage and Handling
Briefly centrifuge the vial upon receipt. An unopened vial may be stored at 2–8°C for up to six months.
Background Information
The cluster of differentiation (CD) system is essential for immunophenotyping, with over 320 unique CD molecules and subclusters identified to date. These CD molecules play various roles in immune cells, either acting as receptors or ligands to initiate signaling cascades that alter cell behavior, or serving non-signaling functions like cell adhesion. CD200 receptor 1 (CD200R1), an isoform of CD200 receptors, is a cell surface glycoprotein expressed on myeloid lineage cells. It serves as a receptor for the OX-2 membrane glycoprotein, and the interaction between CD200R1 and OX-2 functions as a downregulatory signal for myeloid cells, playing a role in immune regulation.
