Human OX40L Protein (N-Fc)

Cat # Size Price Quantity
60470125 ug$145
604702100 ug$295

Product Details


ApplicationELISA, BLI
FormatLiquid, Purified
Expression HostHEK293
Target NameOX40L, TNFSF4, CD252, TXGP1, CD134 ligand, , Glycoprotein Gp34
SpeciesHuman
accession numberP23510
SourcesRecombinant Human OX40L (Gln51-Leu183) with N-terminus Fc tag is expressed in 293 cells
Molecular WeightThis protein has a predicted molecular weight of 41.4 kDa. Under DTT-reducing conditions, the protein migrates at approximately 50 kDa on SDS-PAGE.
Affinity TagN-Fc
Purity>95% based on SDS-PAGE under reducing condition
Formulation1xPBS buffer, pH7.4, 0.22 µm filtered
Endotoxin levelNot tested
Protein Concentration25µg size is bottled at 0.2mg/mL concentration. 100 µg size is supplied at a lot-specific concentration.
Storage and HandlingBriefly centrifuge the vial upon receipt. An unopened vial can be stored at 4°C for up to 2 weeks, or at -20°C or below for up to six months. The protein may be further diluted to 0.1 mg/mL using 0.22 µm-filtered PBS buffer (pH 7.4). For long-term storage, the diluted stock solution should be aliquoted and stored at ≤ –70°C to minimize freeze-thaw cycles. If additional dilution is required, carrier proteins such as FBS or BSA should be added to maintain protein stability.

Background Information


OX40 (also known as CD134) is a costimulatory receptor belonging to the tumor necrosis factor receptor (TNFR) superfamily. Upon binding to its ligand OX40L, OX40 signaling promotes the development of long-lasting memory T cells and sustains immune responses. It is primarily expressed on activated T cells and plays a crucial role in enhancing T cell proliferation, survival, and cytokine production.. Because of its central role in modulating immune activation and tolerance, OX40 is an important target for immunotherapy in cancer, autoimmune diseases, and infectious diseases