Anti-Mouse Ly-6G

Cat # Size Price Quantity
200701100 ug$60
200702500 ug$120

Product Details


Clone1A8
ApplicationFC
ReactivityMouse
FormatPurified
Target NameLy-6G, Lymphocyte antigen 6 complex, locus G, Gr-1
IsotypeRat IgG2a
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Protein Concentration0.5 mg/mL
Storage&HandlingThe antibody solution should be stored between 2°C and 8°C

Background Information


Lymphocyte antigen 6 complex, locus G (Ly-6G), also known as Gr-1, is a 21–25 kDa glycosylphosphatidylinositol (GPI)-anchored surface protein. In mice, it is expressed predominantly on peripheral granulocytes, especially neutrophils, and on the majority of myeloid cells in the bone marrow. Ly-6G is transiently detected on developing monocytes but is stably and highly expressed on mature neutrophils. It plays important roles in neutrophil infiltration, recruitment, and migration, and associates with β2 integrins CD11a and CD11b to regulate their expression and function. The natural ligand for Ly-6G remains unknown, and it is widely used as a specific marker for murine neutrophils in immunological studies.

Data Sheets


Anti-Mouse Ly-6G TDS

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