iF488 Anti-Human CD11b

Product Details


Clone011bAM1
ApplicationFC
ReactivityHuman
FormatiF488
Target NameCD11b, Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM
IsotypeMouse IgG1
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.
Excitation LaserBlue Laser (488 nm)

Background Information


Integrin Alpha M (ITGAM); the alpha subunit of Mac-1 (Macrophage-1 antigen), the CR3 complement receptor which consists of CD11b and CD18. CR3 is a human cell surface receptor, found on polymorphonuclear leukocytes (mostly neutrophils), NK cells, and mononuclear phagocytes like macrophages, which is capable of recognizing and binding to many molecules found on the surfaces of invading bacteria. Binding to the receptor causes phagocytosis and destruction of the foreign cell.

Data Sheets


iF488 Anti-Human CD11b TDS

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