Functional Grade Anti-Mouse CD3

Cat # Size Price Quantity
2002031 mg$150
2002045 mg$450

Product Details


Clone145-2C11
ApplicationFA
ReactivityMouse
FormatLENP
Target NameCD3, T cell antigen receptor complex, T3
IsotypeArmenian Hamster IgG
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, with endotoxin level is less than 0.1Eu/ug as determined by LAL test.
Protein ConcentrationThe 1 mg size is provided at a concentration of 1 mg/mL. Other sizes are supplied at lot-specific concentrations.
Storage and HandlingStore the antibody undiluted at 2°C to 8°C. This LENP-grade (Low Endotoxin, No Preservative) antibody is preservative-free and should be handled using aseptic techniques.

Background Information


CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). CD3 is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Data Sheets


Functional Grade Anti-Mouse CD3 TDS

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