Biotin Anti-Mouse H-2

Product Details


CloneM1/42
ApplicationFC
ReactivityMouse
FormatBiotin
Target NameH-2, major histocompatibility complex (MHC) H-2
IsotypeRat IgG2a
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein Concentration0.5 mg/mL
Storage and HandlingThe antibody solution should be stored between 2°C and 8°C
Recommended UsageFor flow cytometric staining, it is recommended to use less than 0.1 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.

Background Information


Mouse H-2 Complex is the murine equivalent of the human Major Histocompatibility Complex (MHC), located on chromosome 17. It encodes molecules essential for antigen presentation and immune regulation and is divided into: Class I – expressed on all nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes; presents endogenous peptides to CD8⁺ T cells via the CD3/TCR complex, aiding cytotoxic immune responses; Class II – expressed mainly on antigen-presenting cells; presents exogenous peptides to CD4⁺ T cells; Class III – encodes immune-related proteins such as complement components and cytokines.

Data Sheets


Biotin Anti-Mouse H-2 TDS

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