FITC Anti-Mouse TCR β chain

Product Details


CloneH57-597-M2a
ApplicationFC
ReactivityMouse
FormatFITC
Target NameTCR β chain, TCR-β
IsotypeMouse IgG2a
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage and HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.
Excitation LaserBlue Laser (488 nm)

Background Information


The T cell receptor (TCR) is a heterodimeric molecule expressed on the surface of T lymphocytes, responsible for recognizing antigens presented by MHC molecules. In ~95% of T cells, the TCR consists of an α (alpha) and β (beta) chain (αβ TCR), while in ~5% of T cells, it is composed of γ (gamma) and δ (delta) chains (γδ TCR). TCR β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex, which includes CD3 subunits essential for signal transduction. This complex mediates antigen recognition, signal transduction, and subsequent T cell activation.

Data Sheets


FITC Anti-Mouse TCR β chain TDS

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