Anti-Mouse CD11c

Cat # Size Price Quantity
201601100 ug$55
201602500 ug$110

Product Details


CloneN418
ApplicationFC
ReactivityMouse
FormatPurified
Target NameCD11c, integrin αX chain, CR4, ITGAX, p150
IsotypeArmenian Hamster IgG
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Protein Concentration0.5 mg/mL
Storage and HandlingThe antibody solution should be stored between 2°C and 8°C

Background Information


CD11c (Integrin αX, CR4, p150) is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with β2 integrin (CD18) to form the αXβ2 heterodimer. It is expressed mainly on dendritic cells, with additional expression on NK cells, subsets of intestinal intraepithelial lymphocytes, monocytes/macrophages, granulocytes, and some activated T and B cells. CD11c/CD18 binds iC3b, fibrinogen, and CD54 (ICAM-1), mediating cell–cell adhesion, phagocytosis of opsonized particles, and immune cell trafficking.

Data Sheets


Anti-Mouse CD11c TDS

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