Anti-Human HLA-DR

Product Details


CloneL243
ApplicationFC
ReactivityHuman
FormatPurified
Target NameHLA-DR, Major Histocompatibility Class II, MHC class II
IsotypeMouse IgG2a
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Protein Concentration0.5 mg/mL
Storage and HandlingThe antibody solution should be stored between 2°C and 8°C
Recommended UsageFor flow cytometric staining, it is recommended to use less than 0.5 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application

Background Information


HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Data Sheets


Anti-Human HLA-DR TDS

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