Andes Virus Glycoprotein Gn Ectodomain Neutralizing Antibody

Cat #	Size	Price	Quantity
360401	25 μg	$139
360402	100 μg	$339

Bulk/Custom

Product Details

Clone	ANDVDB
Application	ELISA, Neutralization
Reactivity	Andes Virus
Format	Purified
Target Name	Andes virus glycoprotein Gn ectodomain, ANDV Gn, ANDV G1 glycoprotein, ANDV envelope glycoprotein Gn
Isotype	Rabbit IgG
Antibody Type	Monoclonal
Regulatory Status	RUO
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Protein Concentration	0.5 mg/mL
Storage&Handling	The antibody solution should be stored between 2°C and 8°C
Isotype Controls	303301
Antibody Family	Andes Virus Antibodies
See All Formats	Clone ANDVDB

Background Information

Andes virus (ANDV) is an enveloped negative-sense RNA virus belonging to the genus Orthohantavirus within the family Hantaviridae. Andes virus is one of the primary causative agents of hantavirus cardiopulmonary syndrome (HCPS) in South America and is unique among hantaviruses for its documented capability of human-to-human transmission.
The Andes virus glycoprotein precursor (GPC) is proteolytically cleaved into two envelope glycoproteins, Gn and Gc, which assemble into heteromeric spike complexes on the virion surface. The Gn head domain primarily mediates receptor attachment and immune recognition, whereas the Gc glycoprotein functions as a class II fusion protein responsible for membrane fusion during viral entry. The Gn/Gc complex represents a major target for neutralizing antibodies and vaccine development. Recombinant Andes Virus Glycoprotein Gn Head/Gc Complex is widely used in studies of viral entry, structural biology, antibody discovery, epitope mapping, serological assay development, and antiviral therapeutic research.

Learn more about Andes Virus in our detailed Infographic.

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