| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 204101 | 100 ug | $90 | ||
| 204102 | 500 ug | $190 |
| Clone | 2B8 |
|---|---|
| Application | Flow Cytometry |
| Reactivity | Mouse |
| Format | Purified |
| Target Name | CD117, CD-117, c-Kit, Stem Cell Factor Receptor (SCFR) |
| Isotype | Rat IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| See All Formats | Clone 2B8 |
CD117, also known as c-Kit or SCFR, is a 145 kD transmembrane tyrosine-kinase receptor and member of the immunoglobulin superfamily. It functions as a critical receptor for stem cell factor (SCF), activating signaling pathways (e.g., STAT) essential for hematopoiesis, melanogenesis, and gametogenesis.
The protein is primarily expressed on hematopoietic stem cells, mast cells, myeloid progenitors, and certain tumor cells like AML. In analytical applications such as flow cytometry, CD117 antibodies serve as vital markers for identifying multipotent progenitors and studying cell survival, proliferation, and differentiation across various embryonic and mature cell lineages.
Rat IgG2b Isotype Control Antibody
Anti-mouse CD117 (c-Kit) Antibody TDS
iF647 Anti-Mouse CD172a Antibody, Clone P84
Have a product or application question? Consult our FAQs or contact us.
