| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 203501 | 25 ug | $60 | ||
| 203502 | 100 ug | $160 |
| Clone | R1-2 |
|---|---|
| Application | Flow Cytometry |
| Reactivity | Mouse |
| Format | Purified |
| Target Name | CD49d, ITGA4, integrin alpha 4 |
| Isotype | Rat IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.2 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| See All Formats | Clone R1-2 |
CD49d, also known as integrin alpha 4 (ITGA4), is a 150 kDa integrin subunit expressed on a wide range of mouse immune cells, including T and B lymphocytes, monocytes, eosinophils, NK cells, and dendritic cells. CD49d associates with integrin β1 (CD29) to form very late antigen-4 (VLA-4, α4β1) and with integrin β7 to form α4β7 (LPAM-1). These integrins mediate leukocyte adhesion, migration, and tissue homing through interactions with ligands such as VCAM-1, MAdCAM-1, and fibronectin. CD49d also contributes to T cell co-stimulation and plays a key role in inflammatory and immune responses.
Rat IgG2b Isotype Control Antibody
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