APC Anti-Human CD32 (FcγRII) Antibody

Human peripheral blood monocytes stained with either APC Anti-Human CD32 Clone IV.3 (color-filled histogram) or an isotype control (gray histogram).

Cat #	Size	Price	Quantity
109811	25 tests	$115
109812	100 tests	$230

Bulk/Custom

Product Details

Clone	IV.3
Application	Flow Cytometry
Reactivity	Human
Format	APC
Target Name	CD32, FcγRII, FCRII
Isotype	Mouse IgG2b
Antibody Type	Monoclonal
Regulatory Status	RUO
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein Concentration	Supplied at a lot-specific concentration.
Storage&Handling	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended Usage	For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.
Excitation Laser	Red Laser (633 nm)
RRID	AB_3738922
See All Formats	Clone IV.3

Background Information

CD32 is a ~40-kDa polymorphic transmembrane glycoprotein belonging to the immunoglobulin superfamily. Also known as FcγRII or FCRII, it is expressed on a wide variety of immune and blood cells including B cells, monocytes/macrophages, granulocytes, platelets, and it has also been detected on natural killer (NK) cells. There are multiple isoforms of CD32 (at least six produced by alternative mRNA splicing). In humans, the major functional subtypes are CD32A and CD32C (activating) and CD32B (inhibitory).

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