FITC Anti-Human CD79b (Igβ) Antibody

Product Details


ClonePolatuzumab
ApplicationFlow Cytometry
ReactivityHuman
FormatFITC
Target NameCD76b, Igb, Ig-beta, B29
IsotypeHuman IgG1
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. FITC has an excitation max at 493 nm and an emission max at 525 nm.
Excitation LaserBlue Laser (488 nm)
See All FormatsClone Polatuzumab

Background Information


Human CD79B (Igβ, B29) is a 36–40 kDa type I transmembrane glycoprotein expressed on B cells. It forms a heterodimer with CD79A to constitute the B-cell receptor complex, mediating antigen-triggered signaling that regulates B-cell development and activation. Containing an extracellular Ig-like domain and a cytoplasmic ITAM, CD79B is essential for BCR signaling. Mutations cause agammaglobulinemia type 6, and it serves as a diagnostic marker and therapeutic target for B-cell lymphomas.

Isotype Control


FITC Human IgG1 Isotype Control Antibody

Data Sheets


FITC Anti-Human CD79b (Igβ) Antibody TDS

Related Protocols


Flow Cytometry Protocol


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