| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 204105 | 25 tests | $45 | ||
| 204106 | 100 tests | $120 |
| Clone | 2B8 |
|---|---|
| Application | Flow Cytometry |
| Reactivity | Mouse |
| Format | FITC |
| Target Name | CD117, CD-117, c-Kit, Stem Cell Factor Receptor (SCFR) |
| Isotype | Rat IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. FITC has an excitation max at 493 nm and an emission max at 525 nm. |
| Excitation Laser | Blue Laser (488 nm) |
| See All Formats | Clone 2B8 |
CD117, also known as c-Kit or SCFR, is a 145 kD transmembrane tyrosine-kinase receptor and member of the immunoglobulin superfamily. It functions as a critical receptor for stem cell factor (SCF), activating signaling pathways (e.g., STAT) essential for hematopoiesis, melanogenesis, and gametogenesis.
The protein is primarily expressed on hematopoietic stem cells, mast cells, myeloid progenitors, and certain tumor cells like AML. In analytical applications such as flow cytometry, CD117 antibodies serve as vital markers for identifying multipotent progenitors and studying cell survival, proliferation, and differentiation across various embryonic and mature cell lineages.
FITC Rat IgG2b Isotype Control
FITC Anti-mouse CD117 (c-Kit) Antibody TDS
iF647 Anti-Mouse CD172a Antibody, Clone P84
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