| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 203805 | 25 tests | $30 | ||
| 203806 | 100 tests | $80 |
| Clone | PK136 |
|---|---|
| Application | Flow Cytometry |
| Reactivity | Mouse |
| Format | FITC |
| Target Name | NK-1.1, CD161, NKR-P1C, NKR-P1B, Ly-55 |
| Isotype | Mouse IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. FITC has an excitation max at 493 nm and an emission max at 525 nm. |
| Excitation Laser | Blue Laser (488 nm) |
| See All Formats | Clone PK136 |
NK-1.1, also known as CD161b/CD161c or Ly-55, is a type II transmembrane C-type lectin receptor encoded by the Klrb1 (NKR-P1) gene family in mice. It is predominantly expressed on natural killer (NK) cells and a subset of invariant NKT cells in selected mouse strains, including C57BL/6, FVB/N, and NZB. The activating isoform NKR-P1C lacks an inhibitory motif and promotes NK cell cytotoxicity, IFN-γ production, and tumor cell lysis. NK-1.1 expression correlates with effective immune surveillance and graft rejection, making it a widely used marker for identifying and studying murine NK and NKT cell populations.
FITC Mouse IgG2a Isotype Control Antibody
FITC Anti-Mouse NK-1.1 Antibody TDS
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