iF560 Anti-Mouse CD11c (integrin αX) Antibody

Product Details


CloneN418-mG1
ApplicationFlow Cytometry
ReactivityMouse
FormatiF560
Target NameCD11c, integrin αX chain, CR4, ITGAX, p150
IsotypeMouse IgG1
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. iF560 has an excitation max at 560 nm and an emission max at 571 nm.
Excitation LaserGreen/Yellow laser (532/561nm)
See All FormatsClone N418-mG1

Background Information


CD11c (Integrin αX, CR4, p150) is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with β2 integrin (CD18) to form the αXβ2 heterodimer. It is expressed mainly on dendritic cells, with additional expression on NK cells, subsets of intestinal intraepithelial lymphocytes, monocytes/macrophages, granulocytes, and some activated T and B cells. CD11c/CD18 binds iC3b, fibrinogen, and CD54 (ICAM-1), mediating cell–cell adhesion, phagocytosis of opsonized particles, and immune cell trafficking.

Isotype Control


iF560 Mouse IgG1 Isotype Control Antibody

Data Sheets


iF560 Anti-Mouse CD11c (integrin αX) Antibody TDS

Related Protocols


Flow Cytometry Protocol


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