iF647 Anti-Mouse CD11c (integrin αX) Antibody

Product Details


CloneN418-mG1
ApplicationFlow Cytometry
ReactivityMouse
FormatiF647
Target NameCD11c, integrin αX chain, CR4, ITGAX, p150
IsotypeMouse IgG1
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.
Excitation LaserRed Laser (633 nm)
RRIDAB_3739113
See All FormatsClone N418-mG1

Background Information


CD11c (Integrin αX, CR4, p150) is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with β2 integrin (CD18) to form the αXβ2 heterodimer. It is expressed mainly on dendritic cells, with additional expression on NK cells, subsets of intestinal intraepithelial lymphocytes, monocytes/macrophages, granulocytes, and some activated T and B cells. CD11c/CD18 binds iC3b, fibrinogen, and CD54 (ICAM-1), mediating cell–cell adhesion, phagocytosis of opsonized particles, and immune cell trafficking.

Data Sheets


iF647 Anti-Mouse CD11c (integrin αX) Antibody TDS

Related Protocols


Flow Cytometry Protocol

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