| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 111701 | 25ug | $50 | ||
| 111702 | 100 ug | $90 |
| Clone | MQ1-17H12 |
|---|---|
| Application | ICFC, ELISA |
| Reactivity | Human |
| Format | Purified |
| Target Name | IL-2, Interleukin-2, T cell growth factor,Macrophage-activating factor for cytotoxicity I, Killer cell helper factor |
| Isotype | Rat IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.2 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application |
| See All Formats | Clone MQ1-17H12 |
Interleukin-2 (IL-2) is a potent immunomodulatory cytokine primarily produced by activated CD4⁺ T helper cells. It plays a central role in immune activation and tolerance by promoting the proliferation and differentiation of T cells, NK cells, and B cells. IL-2 signals through a heterotrimeric IL-2 receptor complex composed of α (CD25), β, and common γ chains, activating downstream JAK/STAT, PI3K, and MAPK pathways. IL-2 is essential for regulatory T cell development and maintenance, thereby preventing autoimmunity. Human IL-2 shares significant sequence homology with mouse IL-2 and exhibits cross-species activity, supporting its broad application in immunological research and cell culture–based assays
Rat IgG2a Isotype Control Antibody
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